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This offer is redeemable only when accompanied by a valid prescription and is subject to the Terms and Conditions below.

Please click here or scroll down for Indication and Important Safety Information, including Boxed Warning regarding suicidal thoughts and actions. Click here for full Prescribing Information. Click here for the Medication Guide.

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BIN# 019158
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Thank you!

Your APLENZIN Savings Card is now activated!

Congratulations, you are now enrolled!

We will send you a text message to activate your APLENZIN copay card — Reply "Y" to activate your card. You will then receive a text message with a link to add the copay card to the digital wallet on your phone.

Aplenzin Copay Savings Mobile Terms & Conditions

Aplenzin Copay Savings SMS (text) messages are recurring automated copay program messages to receive a digital copay savings card and refill reminders. These SMS messages are sent through PSKW, LLC dba ConnectiveRx, a service provider partner operating on behalf of Bausch Health.

When you opt-in to the service by selecting the radio button and providing your cell phone number, we will send you an SMS message to confirm your signup. By providing your cell phone number, you represent that you are the authorized user of the wireless device you use to receive the messages and that you are authorized to approve any changes. Bausch Health reserves the right to alter these terms and conditions or discontinue the messaging at any time and at its sole discretion, may add or delete a cellular carrier from this program at any time, without notice. Text messages you receive as part of this program are automated and your responses are not read by any person. You are not required to agree to these SMS Terms and Conditions in order to participate in Aplenzin Copay Savings and may opt out at any time. Please visit the Bausch Health privacy policy (https://www.bauschhealth.com/privacy) or contact us for additional information. Please visit the full terms and conditions regarding participation eligibility in Aplenzin Copay Savings (https://www.aplenzin.com).

Message and data rates may apply. While we do not charge you for the messages, your mobile service provider may charge you for SMS text messages as a part of your contract or service. Please contact your mobile service provider for details.

Message frequency varies.

To stop receiving messages, reply STOP at any time.

For help, reply HELP or call 1-844-556-3476.

We are able to deliver on most of the major and minor carriers: i.e., Verizon, Sprint, AT&T, T-Mobile and MetroPCS. If you are unsure whether your carrier supports short codes, please contact your wireless provider directly. Carriers are not liable for delayed or undelivered messages.

BRING YOUR DOWNLOADED CARD TO YOUR PHARMACIST FOR COPAY SAVINGS.

TO THE PATIENT:

  • You must present the card along with your valid prescription to participate in this program.
  • When you use the card you are certifying that you understand and agree to the program rules, regulations, eligibility requirements, and terms and conditions which can be found at www.aplenzin.com.
  • This offer is not valid for any person eligible for reimbursement of prescriptions, in whole or in part, by any federal, state, or other governmental programs, including, but not limited to, Medicare (including Medicare Advantage and Part A, B, and D plans), Medicaid, TRICARE, Veterans Administration or Department of Defense health coverage, CHAMPUS, the Puerto Rico Government Health Insurance Plan, or any other federal or state health care programs.
  • Reimbursement limitations apply, and may vary based on your insurance coverage. Patient is responsible for all additional costs and expenses after maximum limits are reached.

TO THE PHARMACIST: When you use the card, you are certifying that you have not submitted and will not submit a claim for reimbursement under any federal, state, or other governmental programs for this prescription.

Pharmacist instructions for a patient with an Eligible Third-Party Payer

  • Submit the claim to the primary Third Party Payer first, then submit the balance due to SS&C as a Secondary Payer as a copay only billing using BIN 019158 and a valid Other Coverage Code (e.g. 8). The patient is responsible for any amount over the maximum benefit of the card. Reimbursement will be received from SS&C.

For Patients whose insurance plan does not cover product:

  • Submit the claim to the primary Third Party Payer first, then submit the balance due to SS&C as a Secondary Payer as a copay only billing using BIN 019158 and a valid Other Coverage Code (e.g. 3). The patient is responsible for the first $100 and any amount over the maximum benefit of the card. Reimbursement will be received from SS&C.
  • Valid Other Coverage Code required. For any questions regarding SS&C online processing, please call the Help Desk at 1-844-373-0987.
  • Submit transaction using BIN 019158.
  • This offer is only valid for patients with commercial insurance.
  • When you use the card you are certifying that you have not submitted and will not submit a claim for reimbursement under any federal, state, or other governmental programs, including, but not limited to, Medicare (including Medicare Advantage and Part A, B, and D plans), Medicaid, TRICARE, Veterans Administration or Department of Defense health coverage, CHAMPUS, the Puerto Rico Government Health Insurance Plan, or any other federal or state health care programs. The card is not valid for any person eligible for reimbursement of prescriptions, in whole or in part, by any of these programs.
  • By accepting the card and submitting claims for any of the products specified herein you agree to the program terms and conditions, which are posted at www.aplenzin.com.
  • Participants must be 18 years of age or older.
  • This offer expires on 12/31/25.
  • Bausch Health reserves the right to rescind, revoke, terminate, or amend this offer at any time, without notice.

For Privacy Statement, please click here. By submitting your information you confirm you have read and agree with the terms of our Privacy Policy and Legal Notice.

Eligibility Criteria/Terms and Conditions: By using the APLENZIN card, you confirm that you understand and agree to comply with the following terms and conditions of this offer:

  • This offer is only valid for patients with commercial insurance.
  • This offer is not valid for any person eligible for reimbursement of prescriptions, in whole or in part, by any federal, state, or other governmental programs, including, but not limited to, Medicare (including Medicare Advantage and Part A, B, and D plans), Medicaid, TRICARE, Veterans Administration or Department of Defense health coverage, CHAMPUS, the Puerto Rico Government Health Insurance Plan or any other federal or state health care programs.
  • You agree not to seek reimbursement for all or any part of the benefit received through this offer and are responsible for making any required reports of your use of this offer to any insurer or other third party who pays any part of the prescription filled.
  • This offer is good only in the United States of America (including the District of Columbia, Puerto Rico and the U.S. Virgin Islands) at participating retail pharmacies.
  • You must be 18 years of age or older to redeem this offer.
  • You must present the card along with your valid prescription to participate in this program.
  • The card is good for use only with the products identified herein. No other purchase is necessary.
  • This offer cannot be redeemed at government-subsidized clinics.
  • Reimbursement limitations apply, and may vary based on your insurance coverage. The card has a maximum benefit, and the patient is responsible for all additional costs and expenses after maximum benefit limits are reached.
  • The offer is not health insurance.
  • The selling, purchasing, trading, or counterfeiting of the card is prohibited by law. Void if reproduced.
  • This offer is not valid with other offers. The card has no cash value. No cash back. Bausch Health reserves the right to rescind, revoke, terminate, or amend this offer at any time, without notice.
  • You understand and agree to comply with the terms and conditions of this offer as set forth above.
  • This offer expires on 12/31/25.
  • For questions call: 1-844-556-3476.



INDICATION

APLENZIN® (bupropion hydrobromide extended-release tablets) is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder, and for the prevention of autumn-winter seasonal depression (seasonal affective disorder).

IMPORTANT SAFETY INFORMATION

WARNING: CHANGES IN THINKING AND BEHAVIOR, DEPRESSION, AND SUICIDAL THOUGHTS OR ACTIONS

Suicidal Thoughts or Actions and Antidepressant Drugs

Antidepressants may increase the risk of suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment. Depression or other serious mental illnesses are the most important causes of suicidal thoughts and actions. People who have (or have a family history of) bipolar illness or suicidal thoughts or actions may have a particularly high risk. Pay close attention to any changes, especially sudden changes in mood, behaviors, thoughts, or feelings. Call your healthcare provider right away if symptoms such as anxiety, irritability, impulsivity, trouble sleeping, aggressive behavior or suicidal thoughts are new, worse or worry you. APLENZIN has not been evaluated for use in patients under the age of 18.

Call your healthcare provider right away if you or your family member has any of the following symptoms, especially if they are new, worse, or worry you:

  • thoughts about suicide or dying
  • attempts to commit suicide
  • new or worse depression
  • new or worse anxiety
  • feeling very agitated or restless
  • panic attacks
  • trouble sleeping (insomnia)
  • new or worse irritability
  • acting aggressive, being angry, or violent
  • acting on dangerous impulses
  • an extreme increase in activity and talking (mania)
  • other unusual changes in behavior or mood

Although APLENZIN is not a treatment for quitting smoking, it contains the same active ingredient (bupropion) as ZYBAN, which is used to help patients quit smoking.

Some people have had serious side effects while taking bupropion to help them quit smoking, including:

New or worse mental health problems, such as changes in behavior or thinking, aggression, hostility, agitation, depression, or suicidal thoughts or actions. Some people had these symptoms when they began taking bupropion, and others developed them after several weeks of treatment, or after stopping bupropion. These symptoms happened more often in people who had a history of mental health problems before taking bupropion than in people without a history of mental health problems.

Stop taking APLENZIN and call your healthcare provider right away if you, your family, or caregiver notice any of these symptoms. Work with your healthcare provider to decide whether you should continue to take APLENZIN. In many people, these symptoms went away after stopping APLENZIN, but in some people, symptoms continued after stopping APLENZIN. It is important for you to follow-up with your healthcare provider until your symptoms go away.

Before taking APLENZIN, tell your healthcare provider if you have ever had depression or other mental health problems. You should also tell your healthcare provider about any symptoms you had during other times you tried to quit smoking, with or without bupropion.

What Other Important Information Should I Know About APLENZIN?

  • Seizures: There is a chance of having a seizure (convulsion, fit) with APLENZIN, especially in people with certain medical problems or who take certain medicines. Do not take any other medicines while you are taking APLENZIN unless your healthcare provider has said it is okay to take them. If you have a seizure while taking APLENZIN, stop taking the tablets and call your healthcare provider right away.
  • High blood pressure (hypertension): Some people get high blood pressure that can be severe while taking APLENZIN.
  • Manic episodes: Some people may have periods of mania while taking APLENZIN. If you have any of the following symptoms of mania, call your healthcare provider:
    • greatly increased energy
    • severe trouble sleeping
    • racing thoughts
    • reckless behavior
    • unusually grand ideas
    • excessive happiness or irritability
    • talking more or faster than usual
  • Unusual thoughts or behaviors: Some patients may have unusual thoughts or behaviors while taking APLENZIN, including delusions (e.g., believe you are someone else), hallucinations (seeing or hearing things that are not there), paranoia (feeling that people are against you), or feeling confused. If this happens to you, call your healthcare provider.
  • Visual problems: Some people are at risk of glaucoma which can present as: eye pain, changes in vision, or swelling and redness around the eye if they take APLENZIN. You should see an eye doctor to determine whether you are at risk prior to starting therapy.
  • Severe allergic reactions: Some patients have severe allergic reactions to APLENZIN. Stop taking APLENZIN and call your healthcare provider right away if you get a rash, itching, hives, fever, swollen lymph glands, painful sores in the mouth or around the eyes, swelling of the lips or tongue, chest pain, or have trouble breathing. These could be signs of a serious allergic reaction.

Do not take APLENZIN if you:

  • have or had a seizure disorder or epilepsy
  • have or had an eating disorder such as anorexia nervosa or bulimia
  • are taking any other medicines that contain bupropion, including WELLBUTRIN, WELLBUTRIN SR, WELLBUTRIN XL, ZYBAN, or FORFIVO XL. Bupropion is the same active ingredient that is in APLENZIN
  • drink a lot of alcohol and abruptly stop drinking, or use medicines called sedatives (these make you sleepy), benzodiazepines, or anti-seizure medicines, and you stop using them all of a sudden
  • take a monoamine oxidase inhibitor (MAOI). Ask your healthcare provider or pharmacist if you are not sure if you take an MAOI, including the antibiotic linezolid
    • do not take an MAOI within 2 weeks of stopping APLENZIN unless directed to do so by your healthcare provider
    • do not start APLENZIN if you stopped taking an MAOI in the last 2 weeks unless directed to do so by your healthcare provider
  • are allergic to the active ingredient in APLENZIN, bupropion, or to any of the inactive ingredients

Although APLENZIN is not a treatment for quitting smoking, it contains the same active ingredient (bupropion) as ZYBAN, which is used to help patients quit smoking. Before taking APLENZIN, tell your healthcare provider if you have ever had depression, suicidal thoughts or actions, or other mental health problems or any symptoms you had during other times you tried to quit smoking with or without bupropion. Also, tell your healthcare provider about your other medical conditions, including if you:

  • have liver problems, especially cirrhosis of the liver
  • have kidney problems
  • have, or have had, an eating disorder such as anorexia nervosa or bulimia
  • have had a head injury
  • have had a seizure (convulsion, fit)
  • have a tumor in your nervous system (brain or spine)
  • have had a heart attack, heart problems, or high blood pressure
  • are a diabetic taking insulin or other medicines to control your blood sugar
  • drink alcohol
  • abuse prescription medicines or street drugs
  • are pregnant or plan to become pregnant. Talk to your healthcare provider about the risk to your unborn baby if you take APLENZIN during pregnancy, and about registering with the National Pregnancy Registry by calling 1-844-405-6185
  • are breastfeeding. APLENZIN passes into your milk in small amounts

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Many medicines increase your chances of having seizures or cause other serious side effects if you take them while you are using APLENZIN.

The most common side effects of APLENZIN include: trouble sleeping, stuffy nose, dry mouth, dizziness, feeling anxious, nausea, constipation, and joint aches.

Click here to read the Medication Guide carefully before you start using APLENZIN. If you have any questions about APLENZIN, ask your healthcare provider or pharmacist.

Click here for full Prescribing Information, including Medication Guide and Boxed Warning regarding suicidal thoughts and actions.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You may also contact Bausch Health Customer Service at 1-800-321-4576.

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